Postencephalitic parkinsonism – a review
Identifieur interne : 001748 ( Istex/Curation ); précédent : 001747; suivant : 001749Postencephalitic parkinsonism – a review
Auteurs : J. Casals [États-Unis] ; T. S. Elizan [États-Unis] ; M. D. Yahr [États-Unis]Source :
- Journal of Neural Transmission [ 0300-9564 ] ; 1998-09-01.
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Abstract
Summary.: The pandemic of von Economo's disease which began in January 1917 preceded that of influenza of 1918–1919 by more than a year. Though it has been customary to link the two it seems unlikely that the latter was responsible for the former as has been proposed. It has been assumed that von Economo's disease (ED) was caused by a virus; but in fact the etiology is in question as no virus has yet been transmitted to experimental animals or cells in culture. However, the presence of oligoclonal IgG bands in the CSF of suspected cases and the finding of chronic active lesions in the brain tissue at autopsy suggests a viral etiology. Occasional, sporadic presumed cases of the disease have been reported within the last 25 years. Encephalitides due to established neurotropic viruses or to other viruses that may on occasion invade the CNS only rarely produce parkinsonism, and when they do it differs from that seen in ED. The present report reviews the overall concept of a viral etiology of Parkinson's disease with particular reference to von Economo's disease.
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DOI: 10.1007/s007020050086
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Sinai School of Medicine, City University of New York, New York, NY, U.S.A, US</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Mt. Sinai School of Medicine, City University of New York, New York, NY, U.S.A</wicri:regionArea></affiliation></author><author><name sortKey="Yahr, M D" sort="Yahr, M D" uniqKey="Yahr M" first="M. D." last="Yahr">M. D. Yahr</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurology, Mt. Sinai School of Medicine, City University of New York, New York, NY, U.S.A, US</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Mt. 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Sinai School of Medicine, City University of New York, New York, NY, U.S.A, US</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Mt. Sinai School of Medicine, City University of New York, New York, NY, U.S.A</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Neural Transmission</title><title level="j" type="sub">Basic neurosciences and genetics, Parkinson's disease and allied conditions, Alzheimer's disease and related disorders, biological psychiatry</title><title level="j" type="abbrev">J Neural Transm</title><idno type="ISSN">0300-9564</idno><idno type="eISSN">1435-1463</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Wien</pubPlace><date type="published" when="1998-09-01">1998-09-01</date><biblScope unit="volume">105</biblScope><biblScope unit="issue">6-7</biblScope><biblScope unit="page" from="645">645</biblScope><biblScope unit="page" to="676">676</biblScope></imprint><idno type="ISSN">0300-9564</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0300-9564</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Keywords: Postencephalitic parkinsonism</term><term>encephalitis lethargica</term><term>etiology</term><term>primary viral encephalitides.</term><term>von Economo's disease</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Summary.: The pandemic of von Economo's disease which began in January 1917 preceded that of influenza of 1918–1919 by more than a year. Though it has been customary to link the two it seems unlikely that the latter was responsible for the former as has been proposed. It has been assumed that von Economo's disease (ED) was caused by a virus; but in fact the etiology is in question as no virus has yet been transmitted to experimental animals or cells in culture. However, the presence of oligoclonal IgG bands in the CSF of suspected cases and the finding of chronic active lesions in the brain tissue at autopsy suggests a viral etiology. Occasional, sporadic presumed cases of the disease have been reported within the last 25 years. Encephalitides due to established neurotropic viruses or to other viruses that may on occasion invade the CNS only rarely produce parkinsonism, and when they do it differs from that seen in ED. The present report reviews the overall concept of a viral etiology of Parkinson's disease with particular reference to von Economo's disease.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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